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Both Alzheimer and Parkinson's disease are related with the Central Nervous System (CNS). Alzheimer disease is also termed as short term memory loss that results in deficit memory and also affects an individual thinking power and behavior. It's a neurodegenerative disease in which there are progressive deaths of the brain cell that can get worse with passing time. Whereas Parkinson's disease is also known as an Idiopathic or Primary Parkinsonism, as it is a degenerative disorder targeting specifically the motor system responsible for producing dopamine.
The cell death result in the rigidity of the body, shaking, trouble while moving and later can also result in dementia. The abnormality in the chemical substance called dopamine present in brain is the major cause of Alzheimer and Parkinson's. Our drugs are developed to increase the reuptake of dopamine, thereby, reducing the symptoms. Study shows some short term and common side effects associated with the Alzheimer and Parkinson's drugs such as drowsiness, nausea or vomiting, tremor and upset stomach.
Aricept is a drug of choice for the treatment of mild, moderate and severe kind of Alzheimer disease. It contains Donepezil as an active ingredient that shows its action by preventing the breakdown of acetylcholine as it is a reversible inhibitor of this chemical.
On examination the people who are suffering from Alzheimer are diagnosed with less amount of acetylcholine, which is required for the process of thinking, memory and processing. It should be noted that Aricept does not cure Alzheimer while it helps in restoring balance of neurotransmitter in the brain.
Artane is a medicine primarily used for the management of Parkinson’s disease. Its main ingredient Trihexyphenidyl is one of effective centrally acting muscuranic antagonists that are used for relaxation of the stiffness, tremors, spasms and poor muscle control of Parkinson’s disease.
This medicine shows its mechanism by blocking the cholinergic action in CNS which is responsible for the occurrence of the Parkinson’s disease. Furthermore, it also plays an important role in treatment of abnormal muscular condition caused by some of the mentioned drugs like Chlorpromazine, Fluphenazine, Perphenazine, Haloperidol, Thiothixene and many others.
Medicine should be taken as per the direction of the doctor.
While taking medicine, patient can come across some of noted adverse reaction and it is not necessary that everyone can face this.
Dostinex is associated with the treatment of disorder related with high levels of prolactin hormone, either caused by formation of tumor in the pituitary gland or any other cause. Dostinex comprises cabergoline as main drug to show action that belongs to the class of medicine known as prolactin inhibitor.
The mechanism by which this medicine work is related with stimulation of D2 receptor available in anterior pituitary glands, thus prevent the excess production of prolactin. Dostinex is reported to treat different kind of medical problem related with prolactin resulting in menstrual problem and fertility problem in both men and women.
If patient faces any kind of the mentioned unwanted reactions, then he should instantaneously seek the medical assistance.
Eldepryl plays an important role in the management of Parkinson ’s disease. The main active constituent of this medicine is Selegiline as it is an irreversible inhibitor of monoamino oxidase type B (MAO B). Thus, Eldepryl prevents the breakdown of dopamine present in the brain by slowing the mechanism.
Patient diagnosed with the Parkinson’s are prescribed with this medicine in combination with Levodopa or Cabidopa that improvises the tremor, muscle stiffness, loss of normal movement and other activities also.
Exelon has the dual advantage of working in management of both Alzheimer and Parkinson’s disorder. Exelon works by showing its action on preventing the breakdown of acetylcholine in brain required for the process of memory, thinking and progressing.
It basically prescribed to patient having dementia developed due to above mentioned disorders. The main ingredient which composes this medicine is Rivastigmine that does not cure the disease but improvise memory awareness so that patients can do their daily functions normally.
For the management of Parkinson’s disease,Kemadrin is prescribed as therapeutic medicine. Procycline Hydrochloride present in Kemadrin is known for relaxing the smooth muscle, thus controlling the muscle spasm.
The active ingredient is an artificially produced antispasmodic of relatively low toxicity. It is prescribed for the symptomatic treatment of Parkinson’s and extrapyramidal dysfunction reported by tranquilizer therapy. It helps in controlling the stiff muscles, paralysis; trouble related with talking, walking and writing; also prescribed in case of depressed patient.
Most of medicines show the adverse reaction, but the severity depends on patient’s response to medicine. Thus, side effects of Kemadrin is categorize into below mentioned types.
Parkinson’s disease occurs due to the imbalance amount of dopamine in brain.Miraprex works as an agonist of dopamine that helps in restoring its balance. The key element in composition of Miraprex is Pramipexole that can be used alone or in combination with other medication.It accounts in improving ability to move and decrease tremor, stiffness, slowed movement and unsteadiness. In is also used in the management of RLS (Restless Leg Syndrome) that causes an unusual urge to move legs, thereby improving sleep.
While taking Miraprex, patients should take some of the safety measure to avoid any undesirable effect.
In the management of Alzheimer disease,Nameda is included in therapy as it reduces action of chemicals present in brain that may contribute to this syndrome. The key element of the Nameda is Memantine that is used for the treatment of dementia related with Alzheimer. Nameda is NMDA receptor antagonist that shows its mechanism by inhibiting the action of glutamate present in brain. It improvises the memory, thinking power and mental awareness to perform daily functions.
Adult dose for Alzheimer disease
For immediate release:
For extended release:
Call your doctor at once if you have:
Common side effects may include:
The management of Parkinson’s disease can also be done with Parlodel that can be use alone or in combination with other medicine. The key element present in this drug is Bromocriptine mesylate that works by blocking the discharge of prolactin available in pituitary gland.
Parlodel is used in the management of hormonal problem resulted by high level of prolactin that affects the menstrual cycle and fertility in men and women both. In Parkinson disease, Parlodel works by stimulating dopamine receptors in certain parts of the brain.
Galantamine is the main ingredient of Reminyl that improves the function of nerve cells present in brain. Medicine shows it works by preventing the breakdown of a chemical called acetylcholine, the substance involve in the development of dementia. People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning to perform daily function.
Galantamine is a reversible cholinesterase inhibitor for the treatment of mild to moderate level of dementia caused by Alzheimer disease. This medicine works by increasing the concentration of acetylcholine by preventing the hydrolysis of same.
Requip is indicated in idiopathic syndrome of Parkinson’s disease as it mimics the working of dopamine. The signs of Parkinson’s like stiffness of body, shaking and uncontrollable body movements can be controlled by taking this medicine.
Restless Leg Syndrome (RLS) can also be treated with this medicine. It shows it mechanism of action by binding to dopamine receptor in the brain, hence the main component of medicine Ropinorole stimulates the receptor and improvises the condition of Parkinson’s.
Sinemet is the antidyskinetic combination of Carbidopa and Levodopa. The drug is primarily used in the management of idiopathic Parkinson’s and it’s like symptoms such as stiffness, shaking or difficulty in moving the muscle.
Parkinson’s disease mainly occurs when the amount of dopamine in brain gets decreased. Levodopa when reaches the brain gets converted into dopamine, thus controls the symptoms of Parkinson’s. Whereas, Carbidopa prevents the breakdown of levodopa in bloodstream; hence increasing the availability of levodopa in brain.
Sinemet CR is sustained release drug, which is the antidyskinetic combination of Carbidopa and Levodopa. The drug is primarily used in the management of Parkinson’s and it’s like symptoms such as stiffness, shaking or difficulty in moving the muscle. Parkinson’s disease mainly occurs when the amount of dopamine in brain gets decreased.
Levodopa when reaches brain get converted into dopamine, thus controlling the symptoms of Parkinson’s. Whereas, Carbidopa prevents the breakdown of levodopa in bloodstream; hence increasing the availability of levodopa in brain.
Stalevo is an antidyskinetic combination of Carbidopa, Levodopa and Entacopone that is effectively used in the treatment of Parkinson’s disease. Three of them work together by increasing dopamine level in the brain, making it balanced and lessening down the symptoms of disease. Carbidopa when reaches the brain gets converted into levodopa that in turn converted into dopamine, thus increases the amount of dopamine.
Side Effects or adverse effects are the secondary response of drug other than therapeutic one, which causes trouble to patient. All medicines have some kind of their side effects that varies from patient to patient.More common side effects:
Presence of some of the medical conditions can cause harmful consequences if Stalevo is taken. Patient should openly talk to their doctor regarding any of the serious medical history.
Symmetrel is a drug recommended for the treatment of Parkinson’s disease and its symptoms like stiffness and shaking that may be caused by certain drugs. Basically, Symmetrel comprises Amantadine as a basic component which is meant for the treatment of viral infection caused by influenza A. But, this drug has also proven to be effective in treatment of stiffness of the body that occurs in condition of Parkinson’s disease. Its working is believed to be based on blocking the action of virus in body.